SCORE2 no data storage

10-year risk – calibrated by European risk region. SCORE2: 40–69 y; SCORE2-OP: 70–89 y.

Inputs

1 mmol/L = 38.67 mg/dL

Result

10-year risk

This tool does not replace medical advice. Valid for individuals without known cardiovascular disease (and for SCORE2 without diabetes).

What is the SCORE2 Calculator and How Does It Work?

The SCORE2 calculator estimates your individual 10-year risk of cardiovascular events in Europe. It is based on the updated SCORE2 model developed by the European Society of Cardiology (ESC) and incorporates new risk factors such as regional differences, age, and co-existing medical conditions.

What Parameters Does the SCORE2 Calculator Use?

The SCORE2 calculator uses the following parameters to assess your risk:

Parameter Unit Description
Age Years Your age at the time of assessment
Sex Male/Female Risk varies by biological sex
Smoking status Yes/No Whether you currently smoke or not
Systolic blood pressure mmHg Highest measured systolic blood pressure
Total cholesterol mmol/L or mg/dL Total cholesterol level in your blood
HDL cholesterol mmol/L or mg/dL “Good” cholesterol level
Diabetes status Yes/No Presence of type 2 diabetes or prediabetes

These parameters enable precise risk stratification in everyday clinical practice.


How Do You Interpret the SCORE2 Result?

The SCORE2 calculator result is categorized into risk levels:

  • <5% risk: Low cardiovascular risk
  • 5–10% risk: Moderate risk
  • ≥10% risk: High or very high risk

These thresholds depend on age and country. The ESC differentiates between regions: low, moderate, high, and very high risk areas.


What Is Germany’s Risk Category According to SCORE2?

Germany is classified as a moderate-risk region by the ESC SCORE2 model. Calculations should therefore use the region-specific model. Incorrect classification can lead to inappropriate treatment decisions.


How Does SCORE2 Differ from SCORE1?

Feature SCORE1 SCORE2
Introduction 2003 2021
Age Range 40–65 years 40–69 years (SCORE2), 70–89 years (SCORE2-OP)
Mortality Considered Fatal events only Fatal and non-fatal events
Regional Differentiation Uniform Country-specific
Relevance Outdated Current ESC guideline 2021

SCORE2 offers a more accurate prediction through an expanded data set and includes non-fatal cardiovascular events.


How Reliable Is the SCORE2 Prediction?

SCORE2 is based on cohort data from over 700,000 individuals across 45 countries. It has undergone extensive validation, including:

  • International meta-analyses
  • 2021 ESC Guidelines for prevention
  • Comparative studies with the ASCVD Score and Framingham Risk Score

The prediction of cardiovascular mortality and morbidity shows high specificity and sensitivity across Europe.


When Is SCORE2-OP Used?

SCORE2-OP is used for adults aged 70 to 89 years.

Key differences:

  • Higher baseline risk
  • Greater emphasis on multiple co-existing conditions
  • Aims to avoid over- or under-treatment in older adults

Which Clinical Decisions Does the SCORE2 Calculator Support?

The SCORE2 calculator informs decisions about:

  • Starting or adjusting blood pressure treatment
  • Lipid-lowering therapy with statins or ezetimibe
  • Lifestyle interventions (smoking cessation, exercise, nutrition)
  • Intensified cardiovascular management in patients with diabetes

It serves as a decision-making aid in general practice and cardiology.


What Are the Benefits of the Calculator on med-ffm.com?

The SCORE2 calculator on med-ffm.com offers:

  • German-language user interface
  • Simple input without medical expertise
  • Direct risk output with interpretation guide
  • Adjustment to the German risk region
  • Data privacy: no data is stored

This makes it especially useful for doctor consultations and patient education.


How Can You Lower Your Cardiovascular Risk If Your SCORE2 Is High?

Current ESC guidelines recommend the following measures to reduce risk:

  • Smoking cessation: Reduces risk by up to 50% within 12 months
  • Lowering LDL cholesterol: Target <70 mg/dL for high risk
  • Blood pressure control: Target <130/80 mmHg
  • Weight reduction: Target BMI <25
  • Physical activity: At least 150 minutes of moderate exercise per week
  • Medications: Statins, ACE inhibitors, SGLT2 inhibitors if needed for coexisting conditions

These interventions have been shown to significantly reduce long-term risk, as confirmed in clinical trials such as HOPE-3 and EUROASPIRE.


What Are the Limitations of the SCORE2 Calculator?

Despite its high accuracy, SCORE2 has some limitations:

  • Does not account for genetic markers
  • Does not include psychosocial risk factors
  • Limited predictive value in patients under 40 years
  • No dynamic monitoring of risk over time

Therefore, the calculator should always be interpreted in a clinical context and not used in isolation.


What Are the Alternatives to the SCORE2 Model?

Score System Target Group Region Special Features
ASCVD Score USA US Includes family history
PROCAM Score Germany DE Uses triglycerides & LDL
Framingham Risk Score International Global Older model, less specific
QRISK3 UK UK Includes migraine, mental health

SCORE2 remains the recommended standard model in Europe for primary prevention of cardiovascular events.


What Happens After the Risk Calculation?

After entering your data and reviewing your result, the following should take place:

  1. Interpretation together with your doctor
  2. Documentation in your medical records
  3. Treatment adjustments in line with guidelines
  4. Follow-up checks every 1–2 years

A high risk requires immediate action and structured long-term care.


How Often Should You Use the SCORE2 Calculator?

Recommendation: every 5 years for low risk, yearly for high risk. If new risk factors develop (such as a new diagnosis of diabetes or rising blood pressure), recalculate immediately.